Jimmy Kimmel, Simon Baker

Dave announces that today is the 3rd anniversary of his quintuple bypass, and upon mentioning this, Regis interrupts the jokes to give Dave a quick check-up. ""You're screwed,"" Regis proclaims. Throughout the night, Dave reflects on the bypass, claiming he ran five miles six weeks after the bypass. Near the end of the show, Dave tells former announcer Bob Sarlette that his cholesterol is a healthy 46.